FDA Adds 18 Constituents to the List of Harmful and Potentially Harmful Constituents, Seeks Comment on Three Additional Constituents

On April 22, 2026, the U.S. Food and Drug Administration (FDA) published a Federal Register notice finalizing the addition of 18 constituents to the established list of Harmful and Potentially Harmful Constituents (HPHCs) in tobacco products. The HPHC list identifies chemicals and chemical compounds found in tobacco products or tobacco smoke and/or aerosol that cause or could cause harm to users or non-users of tobacco products. Read more here.